Switching from Ozempic to something else?

After 84 lbs gone on Ozempic my appetite suppression has really faded the last couple months and I'm wondering if my body just got used to it. Has anyone here switched to tirzepatide after a long stretch on semaglutide, and did it feel noticeably different? Curious whether the change actually reignited progress for you or if it was more of the same.

I made the same jump after about a year and a half on sema and it did feel different for me, the food noise came back down within a few weeks. That said, I also started logging my meals again around the same time, so like your friend's situation, hard to separate the two. Down 60 myself and the waves pattern held true on both meds.

Two weeks in is really early for a stall, my loss came in waves more than a steady line. I remember panicking around week 3 and then the scale dropped almost overnight a few days later. Tracking protein was honestly what got me moving again too, since my appetite was low enough that I was barely eating anything.

Down 76 myself and I noticed the same fade around the year and a half mark on sema -- the food noise creeping back was what tipped me off. I haven't made the jump to tirz, but the people I know who did said it felt like getting a fresh start rather than just more of the same. At 84 lbs gone you've clearly got the habits down, so even if the med switch only gives a partial boost you're in a decent spot either way.

Down about 60 myself and I've wondered the same thing about adaptation, so watching this one. A friend from my weight loss group made the sema to tirz jump around the two year mark and said the appetite quieted back down within a month, though she also paired it with tightening up her protein tracking, so hard to say how much was the med alone.

Two weeks in is really early, I wouldn't call that a wall yet. I stalled around a month on 0.5 and thought it was over, then the whoosh came a couple weeks later without changing anything. Upping my protein did seem to help keep things moving though.

I'm still early on Wegovy so can't speak to the switch myself, but a couple folks in my local group moved from sema to tirz around the two year mark and both said the food noise came back down within weeks. Seems like the bodies do adapt eventually and tirz hits differently enough to matter. Worth asking your doc about it before the fade stalls you out.

Down 2 so far myself so can't speak to long stalls, but watching this one since I've wondered the same about food noise creeping back after months on sema. Good to hear the jump to tirz actually quieted it for you, even if the logging muddies the cause a bit.

At 14 lbs in I'm way earlier in the journey than you, but the food noise creep already started for me around month five, so I can only imagine 84 lbs in. I haven't switched myself, though the food noise coming back quiet after a tirz jump in here sounds encouraging even with the logging caveat. Following to see how yours shakes out.

At 58 down I hit the same fade around month ten and figured tolerance was the culprit, but tightening my protein at breakfast actually brought the appetite suppression back before I ever considered switching. Might be worth ruling that out first since tirz isn't guaranteed to feel different. The waves pattern the first reply mentioned matched my run too, so some of this may just be the normal rhythm.

I was 80-something down when mine faded too, and honestly the waves never fully stopped, just got shallower. I did end up moving to tirz and the food noise came back quieter for me, but the first few weeks felt like starting over. If I'd known how much a protein-heavy breakfast helped, I might have tried that route first.

The protein angle is worth a shot before jumping, honestly. I was 70 down when things went quiet on me, added more eggs and greek yogurt early in the day and the suppression came back within a couple weeks. Tirz is still on my list if that fades again, but I'd hate to switch and find out it was breakfast all along.

Only 13 lbs into my run so I can't speak to the big-loss fade yet, but the protein-first thing worked for me too when suppression dipped early on. Given you're 84 down, I'd test that for a couple weeks before jumping to tirz, since even the folks here who switched say the first stretch felt like starting over anyway.

I'm only 22 down so I haven't hit the long-haul fade you're describing, but when my suppression dipped early on, keeping protein high and meals on a schedule got me through a rough patch. The folks here who did make the jump mostly got quieter food noise back but paid for it with a rocky ramp-up, so seems like a reasonable order of operations to try the free stuff first.

I switched after about two years on ozempic and yes, tirz felt different for me, food noise got quieter again and I dropped another 15 over the following months. That said the ramp-up was rough and it took a good month to feel normal, so I'd second the protein experiment first since it's free and reversible. If that doesn't move the needle after a few weeks, the switch was worth it in my case.

Same stall happened to my mom at the 2mg mark and she got a decent second wind just bumping protein and tightening her meal timing before ever considering a swap. Tirz was never on the table for her, so I can't compare, but between the stories above about the rough ramp-up it seems like squeezing whatever's left out of the oz first isn't a bad move.

Only 15 lbs in myself so I can't speak to the long-haul fade, but when my appetite dipped early the meal timing and protein thing gave me a real second wind too. Since two people here mentioned the switch costs you a rough ramp-up month anyway, squeezing more out of the oz first seems worth the few weeks before deciding.

Whoosh pattern was my experience too -- two flat weeks early on, then the scale started moving and I'm 32 lbs down now. Two weeks in at 0.5 isn't a wall, it's just your body adjusting. Give it more time before thinking about switching.

Down 43 myself and I hit the same fade around the year mark on oz. Upping protein and being strict about eating windows got me moving again without a switch, so it might be worth ruling that out first. The couple people who did go to tirz here all mentioned a rough first month, which sounds like something you'd want to be ready for if the stall continues.

On tirzepatide now but my semaglutide months looked the same -- nothing for weeks, then a chunk of loss out of nowhere. Six months in, my losses still come in waves, not a steady line. Two weeks is barely a data point.