Fresh Mounjaro question, injecting in a few hours

I've been on Trulicity 4.5 for a while now and down about 9 lbs here in Columbus, and my doctor just cleared me to make the switch to Mounjaro. My first shot is going in tonight and I'm nervous about whether it'll feel stronger than what I'm used to. Anyone else come over from Trulicity and notice a big difference in appetite suppression or side effects that first week?

Made the same kind of jump a while back when I moved up on Wegovy, and the first week definitely hit harder than I expected -- appetite went quiet fast and I had to remind myself to eat something small. I kept dinner light that night and sipped water all evening, which seemed to help. You've already got 9 lbs of experience with this drug class, so trust that you know how your body reacts.

Came over from Trulicity myself and the first Mounjaro shot felt smoother than I braced for, just quieter appetite that actually lasted. The 76 lbs I'm down now started with that kind of nervous first night, so you'll likely be fine keeping dinner light like you probably did on Trulicity. curious what the appetite difference feels like to you after a few days.

Are you pairing it with any walking or strength work? This is huge.

Made the same Trulicity-to-Mounjaro move last year and the first shot honestly felt less dramatic than I feared, mostly just steadier appetite quiet that stuck around longer between meals. The 60 lbs I'm down now started with that same nervous first night, so I get it. Just keep some easy food on hand like you probably already did on Trulicity.

I'm on semaglutide so can't speak to that exact switch, but the day 2-3 thing tracks with my experience too -- night one felt like nothing and then the appetite quiet crept in over the next couple days. Eat something tonight even if you don't feel like it, that's the mistake I made my first week.

Switched from Trulicity too and the Mounjaro shot itself felt no worse, the main thing I noticed was the appetite quiet lasting well past where Trulicity always wore off for me. Day 2-3 was when I really felt it, so don't judge off night one. That carried me through my 36 lbs so far.

Came over from Trulicity too and night one was a non-event for me, the quieter appetite showed up around day 3 and stuck way longer between meals than I was used to. I made the mistake of skipping dinner that first night, so definitely eat something even if nothing sounds good. Congrats on getting cleared for the switch!

Made the same jump from Trulicity and my first night was pretty uneventful too. By day 3 I could tell the appetite quiet was lasting way longer between meals than I ever got before, which is honestly where most of my 20 lbs came off. I ate dinner that first night since I'd heard others regret skipping it, so glad you got that heads up already.

Another Trulicity switcher here and same story -- shot one felt like nothing, then around day 3 I noticed food just lost its grip in a way Trulicity never did for me. I forced down dinner that first night and I think that saved me, since I'd read too many regret posts. Down 21 lbs since switching and the first week nerves were way worse than the actual week.

Made the same switch and night one was honestly boring, then day 3 hit and meals started sticking with me for hours longer than Trulicity ever managed. Definitely eat dinner tonight regardless of appetite, that one saved me. The first-week nerves were the worst part for me too.

Switched from Trulicity myself and the first shot was a non-event, the real shift hit around day three when I realized I'd forgotten about lunch entirely. I made myself eat something that night too even with zero interest in food, and my stomach thanked me for it. Down 12 lbs so far, so no complaints.

Switched from Trulicity too and my first Mounjaro shot was a total snooze, the appetite quieting kicked in for me around day 3 or 4. The one thing I'm glad I did was eat a real dinner that first night even though nothing sounded good -- felt way better the next morning because of it. Down 34 lbs since the swap, so the nerves tonight are the hardest part, not the week itself.

Trulicity to Mounjaro here too, and same story -- quiet first night, then the appetite effect showed up a few days in. I forced some food down that first evening even though I didn't want it, and I think that's why the next day went smooth. You've already got 9 lbs of proof you can do this, the nerves are the worst part.

Made the same jump from Trulicity and honestly the shot itself felt easier, not stronger. I second the eating-a-real-dinner-first-night thing -- my appetite didn't really drop until a few days later anyway. Down about 15 since switching, so the swap has worked out well for me.

Same here, the second week was my wall and then one morning I just realized I'd eaten a full dinner without thinking about it. Post after post in this thread matching that pattern says a lot. Hope the next shot goes just as smooth.

Made the same jump and the injection itself was a non-event, nothing like the stronger hit I was bracing for. My appetite quieted down a few days later too. For what it's worth I'm 60 lbs into this whole thing now and the switch was one of the better calls along the way.

Interesting that everyone here hit the wall around week two, because mine was week three before it broke. Either way, the food noise fading so gradually I didn't notice it until dinner one night was the real turning point for me. Glad you're on the smooth part of the curve now.