Zepbound

tirzepatide · Dual GIP / GLP-1 receptor agonist

What it is

Zepbound is a brand name for tirzepatide dosed for weight management. It is the same dual GIP/GLP-1 molecule as Mounjaro, offered as a once-weekly injectable for a different approved use.

What it's used for

FDA-approved for chronic weight management in adults with obesity or overweight with at least one weight-related condition, and for moderate-to-severe obstructive sleep apnea in adults with obesity. Used with reduced-calorie eating and more physical activity.

Typical dosing schedule

Dosing schedules differ by person and are set by a prescriber. The pattern below is a commonly described escalation — it is informational only, not a recommendation.

DoseTypical timingNotes
2.5 mgWeeks 1–4Starting dose.
5 mgWeeks 5–8First maintenance option.
7.5 mgAs directedStep up if needed.
10 mgAs directedStep up if needed.
12.5–15 mgAs directedHigher maintenance doses.

Common side effects

Commonly reported side effects include nausea, diarrhea, constipation, vomiting, abdominal pain, fatigue, and injection-site reactions during titration. Many people find symptoms ease over time, but persistent or severe symptoms should always be discussed with your prescriber. See our side-effects guide for management tips members commonly share.

Rough cost

Roughly $1,000–$1,300/month at US list price without insurance; manufacturer savings and self-pay vial programs may lower cost for eligible patients.

Pricing varies widely. See our cost & insurance guide for savings programs, prior-authorization basics, and more.

Discuss it with the community

Read real member experiences and ask questions: