JA
Member
JoinedMay 14, 2026
Messages10
I'm a nurse and I want to share a clinical perspective on the GI side effects. What's happening in your gut during the first few weeks is the medication slowing gastric emptying significantly. This is by design — it's the mechanism that creates satiety. The nausea is your body adjusting to this new normal. It gets better as your body adapts.
SH
Member
JoinedJun 10, 2026
Messages10
Starting the weight-loss log here because I need accountability. Starting weight: 278 lbs. Goal: 195 lbs. Week 1 on 0.25mg semaglutide. No real side effects yet, just a slightly off stomach on injection day. Will update every Monday.
TI
Moderator
JoinedMay 13, 2026
Messages10
I was terrified of the needle too. Now it takes me about 30 seconds on Sunday mornings.
FA
Member
JoinedMay 08, 2026
Messages10
Solidarity from someone who's been through the exact same thing. You've got this.
PE
Member
JoinedMay 04, 2026
Messages10
Starting the weight-loss log here because I need accountability. Starting weight: 278 lbs. Goal: 195 lbs. Week 1 on 0.25mg semaglutide. No real side effects yet, just a slightly off stomach on injection day. Will update every Monday.
PR
Member
JoinedMay 21, 2026
Messages10
The tiredness in week 2 is very real. Be patient with yourself.