GL
Moderator
JoinedJun 03, 2026
Messages11
My doc kept me at 0.5mg for almost 3 months because I was losing well and tolerating it fine. I pushed back a bit because I'd read about faster titration schedules, but looking back I'm glad she slowed it down. Zero serious side effects the whole time. Anyone else had a similar experience with a conservative titration?
AU
Member
JoinedJun 04, 2026
Messages10
Six-month check-in thread for anyone who wants to follow along:
Month 1 (0.25mg): Down 11 lbs. Mostly water weight plus the early loss. Nausea was rough days 2-4 after injection but manageable with small meals.
Month 2 (0.5mg): Down 8 more lbs. Found my rhythm. Protein first at every meal. Nausea basically gone by week 6.
Month 3 (0.5mg still): Stall. 3 weeks, scale didn't move. Measurements did. Pushed through.
Month 4 (1mg): Stall broke at the new dose. Down 9 lbs this month.
Month 5 (1mg): Steady loss, 6 lbs. Starting to feel like maintenance territory.
Month 6 (1mg): Current status. Total: -41 lbs. Energy is excellent. Food relationship completely transformed. Would recommend to anyone who qualifies.
SE
Member
JoinedMay 23, 2026
Messages10
The mental shift is real and nobody talks about it enough. By month 3 I stopped thinking about food constantly. I'd walk past a donut shop and feel nothing. That's not willpower — that's the medication working on a neurological level. I genuinely feel like a different person and it's still a bit surreal.
LO
Member
JoinedJun 17, 2026
Messages10
Full 9-month honest review since I hit my goal weight last week. Started at 312 lbs, currently 224 lbs — 88 lbs down. Semaglutide from month 1-5, switched to tirzepatide at month 5 when I stalled. The switch broke the stall within 3 weeks.
Side effects were rough months 1-2. I lost 8 lbs in the first month just because I couldn't eat. Everything improved by month 3 and I found my rhythm: injection Sunday evening, light dinner that night, protein-heavy meals the rest of the week.
What I wish I'd known: start strength training immediately. I lost muscle in the first few months and it was hard to rebuild. If I were starting over I'd have a personal trainer from day one. The medication handles the appetite; you have to handle the exercise.
Bottom line: this is the most effective thing I've ever done for my health. My A1C dropped from 7.1 to 5.4, my blood pressure is normal, and I sleep better than I have in years. It's a tool, not a magic pill, but it's an extraordinary tool.
WI
Member
JoinedMay 29, 2026
Messages10
Starting the weight-loss log here because I need accountability. Starting weight: 278 lbs. Goal: 195 lbs. Week 1 on 0.25mg semaglutide. No real side effects yet, just a slightly off stomach on injection day. Will update every Monday.
IN
Member
JoinedMay 13, 2026
Messages10
The sulfur burps are embarrassing but Pepto and Gas-X got me through the worst weeks.