10mg tirzepatide — strongest appetite suppression I've felt

I'm a nurse and I want to share a clinical perspective on the GI side effects. What's happening in your gut during the first few weeks is the medication slowing gastric emptying significantly. This is by design — it's the mechanism that creates satiety. The nausea is your body adjusting to this new normal. It gets better as your body adapts.

Coming back to this thread, Just hit my first 20 lbs and I can't believe it. You're not alone in this, so many of us have been there. Just hit my first 20 lbs and I can't believe it. So glad I'm not alone in this. Definitely run it by your own prescriber though.

Adding my two cents: You should be really proud. What's your current titration schedule looking like. I plan my meals around shot-day appetite changes now. Onward!

Totally agree. Clothes are loose enough that I need a smaller size. Thanks for sharing this.

I keep a protein shake on my desk for days when nothing sounds good. It helps.

Honestly, Don't weigh daily, the trend line is what matters.

The jump to the next dose was smoother than I feared. Did your appetite come back at all on the higher dose.

Honestly, We're all in this together. You've got this.

Week 12 checking in — yes, the hair loss is real but it does slow down. Biotin helped me.

How long did the food noise take to quiet down. Consistency with my injection day mattered more than the exact dose. Rooting for you. (Not medical advice, just my own experience.)

This is exactly what happened to me at week 6. The nausea just... stopped one day. Hang in there!

Following along, Hit a number on the scale this morning I haven't seen in years. Ugh I felt exactly the same way at that stage. Hang in there.

Just wanted to say, This made my day to read. This community is the best. (Not medical advice, just my own experience.)

Totally agree. Just hit my first 20 lbs and I can't believe it. I plateaued until the dose increase kicked things back in gear. I plan my meals around shot-day appetite changes now. Definitely run it by your own prescriber though.

Following along, Scale didn't move but my rings fit again. You're doing amazing. The mental side is harder than people admit.

This is exactly what happened to me at week 6. The nausea just... stopped one day. Hang in there!

Following along, You're not alone in this, so many of us have been there. Onward! Everyone's different of course.

Following along — I plan my meals around shot-day appetite changes now. I plan my meals around shot-day appetite changes now. So glad I'm not alone in this.

What helped you push through the plateau. Six months in and down 41 lbs total.

Same here, This is huge. Batch-cooking high-protein meals saved my willpower. Keep us posted!